Polyunsaturated Phosphatidylcholine in NT FactorTM Improves Mitochondrial Function, Auditory Sensitivity and may Slow some of the Aging Processes
نویسنده
چکیده
H The purpose of this study was to investigate the effects of polyunsaturated phosphatidylcholine (PPC) in NT FactorTM* on aging, in general, and ageassociated hearing loss, in specific. Additionally, this brief report supports that the Membrane Hypothesis of Aging (MHA) provides a plausible explanation for agerelated hearing loss. According to this hypothesis, which is also known as the Mitochondrial Clock Theory of Aging, Reactive Oxygen Metabolites (ROM), are responsible for progressive insults on mitochondria and other cellular structures. Over an extended time period, these insults accumulate leading to a reduction in the energy generating capacity of the mitochondria, cellular demise and resultant senescence. Soy lecithin is a source from which PPC can be extracted. These molecules are indispensable for cellular differentiation, proliferation and
منابع مشابه
Influence of lecithin on mitochondrial DNA and age-related hearing loss.
OBJECTIVES Lecithin is a polyunsaturated phosphatidylcholine (PPC), which are high energy functional and structural elements of all biologic membranes. PPC play a rate-limiting role in the activation of numerous membrane-located enzymes, including superoxide dismutase and glutathione, which are important antioxidants protecting cell membranes from damage by reactive oxygen species (ROS). ROS-in...
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